Disease-specific profiles of apathy in Alzheimer’s disease and behavioural-variant frontotemporal dementia differ across the disease course
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09679-1
Abstract: Apathy is one of the most prevalent and disabling non-cognitive symptoms of dementia. This loss of motivation and pervasive decline in goal-directed behaviour represents a core diagnostic feature of behavioural-variant frontotemporal dementia (bvFTD) and is… read more here.
Keywords: dementia; disease; variant frontotemporal; disease course ... See more keywords
Visuospatial dysfunction in Alzheimer's disease and behavioural variant frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2019.04.019
Abstract: OBJECTIVES Approximately 30% of Alzheimer's disease (AD) patients are misdiagnosed due to overlapping and evolving clinical features. In particular, the distinction of AD from behavioural variant frontotemporal dementia (bvFTD) can be challenging. Measures of visuospatial… read more here.
Keywords: frontotemporal dementia; alzheimer disease; disease; variant frontotemporal ... See more keywords
Disease trajectories in behavioural variant frontotemporal dementia, primary psychiatric and other neurodegenerative disorders presenting with behavioural change.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2018.07.014
Abstract: Behavioural variant frontotemporal dementia (bvFTD) is characterized by behavioural and social cognitive disturbances, while various psychiatric and neurodegenerative disorders may have similar clinical symptoms. Since neurodegenerative disorders are eventually progressive, whereas primary psychiatric disorders are… read more here.
Keywords: change; neurodegenerative disorders; disease trajectories; primary psychiatric ... See more keywords
Neurofilament light chain as a blood biomarker to differentiate psychiatric disorders from behavioural variant frontotemporal dementia.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2019.03.019
Abstract: The overlapping symptoms of behavioural variant frontotemporal dementia (bvFTD) and primary psychiatric disorders (such as depressive disorder, schizophrenia spectrum, and bipolar disorder) present a challenge for the differential diagnosis of bvFTD in middle and older-aged… read more here.
Keywords: bvftd; psychiatric disorders; biomarker differentiate; behavioural variant ... See more keywords
Reward deficits in behavioural variant frontotemporal dementia include insensitivity to negative stimuli
Sign Up to like & getrecommendations! Published in 2017 at "Brain"
DOI: 10.1093/brain/awx259
Abstract: During reward processing individuals weigh positive and negative features of a stimulus to determine whether they will pursue or avoid it. Though patients with behavioural variant frontotemporal dementia display changes in their pursuit of rewards,… read more here.
Keywords: frontotemporal dementia; patients behavioural; variant frontotemporal; reward ... See more keywords
Predictors of survival and progression in behavioural variant frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13887
Abstract: Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. read more here.
Keywords: frontotemporal dementia; variant frontotemporal; predictors survival; progression ... See more keywords
Clinical features of the behavioural variant of frontotemporal dementia that are useful for predicting underlying pathological subtypes of frontotemporal lobar degeneration
Sign Up to like & getrecommendations! Published in 2018 at "Psychogeriatrics"
DOI: 10.1111/psyg.12334
Abstract: The behavioural variant of frontotemporal dementia (bvFTD) is the most common phenotype of frontotemporal lobar degeneration (FTLD). FTLD is divided into three main pathological subtypes: tau‐positive FTLD (FTLD‐tau), FTLD‐TAR DNA–binding protein (TDP), and FTLD‐Fused in… read more here.
Keywords: frontotemporal dementia; ftld; pathological subtypes; variant frontotemporal ... See more keywords
A caregiver's perspective on clinically relevant symptoms in behavioural variant frontotemporal dementia: tools for disease management and trial design
Sign Up to like & getrecommendations! Published in 2022 at "Psychogeriatrics"
DOI: 10.1111/psyg.12898
Abstract: Adequate detection of symptoms and disease progression in behavioural variant frontotemporal dementia (bvFTD) is complex. Dementia cohorts usually utilize cognitive and functional measures, which fail to detect dominant behavioural and social cognitive deficits in bvFTD.… read more here.
Keywords: variant frontotemporal; caregiver perspective; behavioural variant; relevant symptoms ... See more keywords
Diagnosing, monitoring and managing behavioural variant frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2017 at "Medical Journal of Australia"
DOI: 10.5694/mja16.01458
Abstract: Behavioural variant frontotemporal dementia is characterised by insidious changes in personality and interpersonal conduct that reflect progressive disintegration of the neural circuits involved in social cognition, emotion regulation, motivation and decision making. The underlying pathology… read more here.
Keywords: frontotemporal dementia; variant frontotemporal; diagnosing monitoring; monitoring managing ... See more keywords
Lessons of the month: HLA-B27-associated syndrome and spontaneous intracranial hypotension resulting in behavioural variant frontotemporal dementia.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical medicine"
DOI: 10.7861/clinmed.2020-0062
Abstract: Spontaneous intracranial hypotension is uncommon and results from a cerebrospinal fluid (CSF) leak. We describe the case of a marathon runner who presented with postural headache attributable to CSF venous fistulation originating from a lower… read more here.
Keywords: b27 associated; intracranial hypotension; associated syndrome; variant frontotemporal ... See more keywords