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   Articles with "behavioural variant" as a keyword



Disease-specific profiles of apathy in Alzheimer’s disease and behavioural-variant frontotemporal dementia differ across the disease course

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recommendations! Published in 2019 at "Journal of Neurology"

DOI: 10.1007/s00415-019-09679-1

Abstract: Apathy is one of the most prevalent and disabling non-cognitive symptoms of dementia. This loss of motivation and pervasive decline in goal-directed behaviour represents a core diagnostic feature of behavioural-variant frontotemporal dementia (bvFTD) and is… read more here.

Keywords: dementia; disease; variant frontotemporal; disease course ... See more keywords

Visuospatial dysfunction in Alzheimer's disease and behavioural variant frontotemporal dementia

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recommendations! Published in 2019 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2019.04.019

Abstract: OBJECTIVES Approximately 30% of Alzheimer's disease (AD) patients are misdiagnosed due to overlapping and evolving clinical features. In particular, the distinction of AD from behavioural variant frontotemporal dementia (bvFTD) can be challenging. Measures of visuospatial… read more here.

Keywords: frontotemporal dementia; alzheimer disease; disease; variant frontotemporal ... See more keywords

Disease trajectories in behavioural variant frontotemporal dementia, primary psychiatric and other neurodegenerative disorders presenting with behavioural change.

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recommendations! Published in 2018 at "Journal of psychiatric research"

DOI: 10.1016/j.jpsychires.2018.07.014

Abstract: Behavioural variant frontotemporal dementia (bvFTD) is characterized by behavioural and social cognitive disturbances, while various psychiatric and neurodegenerative disorders may have similar clinical symptoms. Since neurodegenerative disorders are eventually progressive, whereas primary psychiatric disorders are… read more here.

Keywords: change; neurodegenerative disorders; disease trajectories; primary psychiatric ... See more keywords

Neurofilament light chain as a blood biomarker to differentiate psychiatric disorders from behavioural variant frontotemporal dementia.

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recommendations! Published in 2019 at "Journal of psychiatric research"

DOI: 10.1016/j.jpsychires.2019.03.019

Abstract: The overlapping symptoms of behavioural variant frontotemporal dementia (bvFTD) and primary psychiatric disorders (such as depressive disorder, schizophrenia spectrum, and bipolar disorder) present a challenge for the differential diagnosis of bvFTD in middle and older-aged… read more here.

Keywords: bvftd; psychiatric disorders; biomarker differentiate; behavioural variant ... See more keywords

Reward deficits in behavioural variant frontotemporal dementia include insensitivity to negative stimuli

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recommendations! Published in 2017 at "Brain"

DOI: 10.1093/brain/awx259

Abstract: During reward processing individuals weigh positive and negative features of a stimulus to determine whether they will pursue or avoid it. Though patients with behavioural variant frontotemporal dementia display changes in their pursuit of rewards,… read more here.

Keywords: frontotemporal dementia; patients behavioural; variant frontotemporal; reward ... See more keywords
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Predictors of survival and progression in behavioural variant frontotemporal dementia

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recommendations! Published in 2019 at "European Journal of Neurology"

DOI: 10.1111/ene.13887

Abstract: Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. read more here.

Keywords: frontotemporal dementia; variant frontotemporal; predictors survival; progression ... See more keywords

Factors associated with true‐positive and false‐positive diagnoses of behavioural variant frontotemporal dementia in 100 consecutive referrals from specialist physicians

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recommendations! Published in 2025 at "European Journal of Neurology"

DOI: 10.1111/ene.70036

Abstract: The behavioural variant of frontotemporal dementia (bvFTD) is a challenging diagnosis due to overlapping symptoms with psychiatric and other neurological conditions. Accordingly, misdiagnosis is common. The present study aimed to identify clinical factors contributing to… read more here.

Keywords: frontotemporal dementia; variant frontotemporal; behavioural variant; factors associated ... See more keywords

Clinical features of the behavioural variant of frontotemporal dementia that are useful for predicting underlying pathological subtypes of frontotemporal lobar degeneration

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recommendations! Published in 2018 at "Psychogeriatrics"

DOI: 10.1111/psyg.12334

Abstract: The behavioural variant of frontotemporal dementia (bvFTD) is the most common phenotype of frontotemporal lobar degeneration (FTLD). FTLD is divided into three main pathological subtypes: tau‐positive FTLD (FTLD‐tau), FTLD‐TAR DNA–binding protein (TDP), and FTLD‐Fused in… read more here.

Keywords: frontotemporal dementia; ftld; pathological subtypes; variant frontotemporal ... See more keywords

A caregiver's perspective on clinically relevant symptoms in behavioural variant frontotemporal dementia: tools for disease management and trial design

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recommendations! Published in 2022 at "Psychogeriatrics"

DOI: 10.1111/psyg.12898

Abstract: Adequate detection of symptoms and disease progression in behavioural variant frontotemporal dementia (bvFTD) is complex. Dementia cohorts usually utilize cognitive and functional measures, which fail to detect dominant behavioural and social cognitive deficits in bvFTD.… read more here.

Keywords: variant frontotemporal; caregiver perspective; behavioural variant; relevant symptoms ... See more keywords

Quantity and Quality Matter: Different Neuroanatomical Substrates of Apathy in Alzheimer’s Disease and Behavioural Variant Frontotemporal Dementia

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recommendations! Published in 2025 at "Brain Sciences"

DOI: 10.3390/brainsci15050447

Abstract: Background: Apathy is almost ubiquitous across neurodegenerative diseases and can be a general model for understanding neuropsychiatric symptoms in dementia. Methods: We assessed apathy via Starkstein’s Apathy Scale—caregiver version (SAS-C) in patients with Alzheimer’s disease… read more here.

Keywords: frontotemporal dementia; alzheimer disease; variant frontotemporal; behavioural variant ... See more keywords

Diagnosing, monitoring and managing behavioural variant frontotemporal dementia

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recommendations! Published in 2017 at "Medical Journal of Australia"

DOI: 10.5694/mja16.01458

Abstract: Behavioural variant frontotemporal dementia is characterised by insidious changes in personality and interpersonal conduct that reflect progressive disintegration of the neural circuits involved in social cognition, emotion regulation, motivation and decision making. The underlying pathology… read more here.

Keywords: frontotemporal dementia; variant frontotemporal; diagnosing monitoring; monitoring managing ... See more keywords