Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300070
Abstract: PRDM16 (PR domain containing protein 16) serves as a dominant activator of brown and beige adipocyte. However, mechanisms underlying the regulation of PRDM16 expression are incompletely understood. A Prdm16 luciferase knockin reporter mouse model is generated, enabling high… read more here.
Keywords: prdm16; androgen receptor; beige adipocyte; expression ... See more keywords
Impaired adrenergic agonist‐dependent beige adipocyte induction in aged mice
Sign Up to like & getrecommendations! Published in 2017 at "Obesity"
DOI: 10.1002/oby.21727
Abstract: There are two types of thermogenic adipocytes expressing uncoupling protein (UCP)−1: the brown adipocyte activated by adrenergic stimulation and the beige adipocyte that appears within the white adipose tissue (WAT) in response to chronic adrenergic… read more here.
Keywords: adrenergic agonist; adipocyte; adrenergic stimulation; impaired adrenergic ... See more keywords
Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2020.07.011
Abstract: Abstract Cynandione A (CA) is a major ingredient of Cynanchum wilfordii. Here, we report a new function of CA in adipogenesis in 3T3-L1 cells, a preadipocyte cell line. During adipogenic differentiation in 3T3-L1 cells, CA… read more here.
Keywords: adipocyte; adipocyte related; beige adipocyte; induces adipogenesis ... See more keywords
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1006950
Abstract: Given the relevance of beige adipocytes in adult humans, a better understanding of the molecular circuits involved in beige adipocyte biogenesis has provided new insight into human brown adipocyte biology. Genetic mutations in SLC39A13/ZIP13, a… read more here.
Keywords: zinc transporter; beige adipocyte; adipocyte biogenesis; zip13 ... See more keywords
Anthocyanins and Curcumin: Possible Abilities of Prevention of Diabetes and Obesity via Stimulation of Glucagon-Like Peptide-1 Secretion and Induction of Beige Adipocyte Formation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.68.s110
Abstract: There is growing interest in the health benefits of natural plant pigments such as anthocyanins and curcumin. In this review, we introduce how these pigments can contribute to the prevention of diabetes and obesity by… read more here.
Keywords: secretion; beige adipocyte; prevention diabetes; adipocyte formation ... See more keywords
Liensinine Inhibits Beige Adipocytes Recovering to white Adipocytes through Blocking Mitophagy Flux In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2019 at "Nutrients"
DOI: 10.3390/nu11071640
Abstract: Promoting white-to-beige adipocyte transition is a promising approach for obesity treatment. Although Liensinine (Lie), a kind of isoquinoline alkaloid, has been reported to affect white-to-beige adipocyte transition, its effects on inhibiting beige adipocytes recovering to… read more here.
Keywords: recovering white; white adipocytes; adipocytes recovering; beige adipocytes ... See more keywords
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.77102
Abstract: Brown and beige fat protect against cold environments and obesity by catabolizing stored energy to generate heat. This process is achieved by controlling thermogenesis-related gene expression and the development of brown/beige fat through the induction… read more here.
Keywords: ppar; expression; sox4; beige adipocyte ... See more keywords