H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA.
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DOI: 10.1016/j.bbrc.2019.09.082
Abstract: Currently, 5-fluorouracil (5-FU) resistance became a major obstacle to its clinical use for patients with hepatocellular carcinoma (HCC). It's urgent to develop a novel strategy for enhancing the therapeutic efficacy of 5-FU. Herein, we found… read more here.
Keywords: bel7402 cells; inducing puma; cells via; derivative tetrandrine ... See more keywords