A time-resolved interaction analysis of Bem1 reconstructs the flow of Cdc42 during polar growth
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DOI: 10.26508/lsa.202000813
Abstract: A temporal dissection correlates changes in composition and architecture of the interaction network of Bem1 with changes in cellular morphology and the activities of its binding partners. Cdc42 organizes cellular polarity and directs the formation… read more here.
Keywords: cdc42; bem1; analysis; cell cycle ... See more keywords
Scaffold-mediated gating of Cdc42 signalling flux
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DOI: 10.7554/elife.25257
Abstract: Scaffold proteins modulate signalling pathway activity spatially and temporally. In budding yeast, the scaffold Bem1 contributes to polarity axis establishment by regulating the GTPase Cdc42. Although different models have been proposed for Bem1 function, there… read more here.
Keywords: cdc42; signalling flux; scaffold mediated; gef activity ... See more keywords