Potential of flavonoids as anti-Alzheimer’s agents: bench to bedside
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-18165-z
Abstract: Developing therapies for neurodegenerative diseases are challenging because of the presence of blood–brain barrier and Alzheimer being one of the commonest and uprising neurodegenerative disorders possess the need for developing novel therapies. Alzheimer’s is attributed… read more here.
Keywords: anti alzheimer; agents bench; bench bedside; flavonoids anti ... See more keywords
Novel Biomarkers in Sinonasal Cancers: from Bench to Bedside
Sign Up to like & getrecommendations! Published in 2020 at "Current Oncology Reports"
DOI: 10.1007/s11912-020-00947-2
Abstract: Sinonasal cancers are a heterogenous group of rare cancers for which histopathological diagnosis can be very challenging and treatment options are limited for advanced disease in particular. Here, we review the candidacy of novel diagnostic… read more here.
Keywords: cancers bench; sinonasal cancers; novel biomarkers; bench bedside ... See more keywords
Endometrial CRH and implantation: from bench to bedside
Sign Up to like & getrecommendations! Published in 2018 at "Hormones"
DOI: 10.1007/s42000-018-0042-4
Abstract: Endometrial corticotropin-releasing hormone (CRH) has been described as a mediator of decidualisation and as a contributor of maternal–fetal immunotolerance. Deregulation of the CRH expression pattern has been associated with unfavourable reproductive outcomes as well as… read more here.
Keywords: endometrial crh; implantation bench; crh; bench bedside ... See more keywords
Oncofertility: What can we do from bench to bedside?
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.10.023
Abstract: Continuous improvement in diagnosis and treatment has significantly increased the survival of cancer patients. Treatments for neoplastic disease, including radiotherapy, chemotherapy, and surgery or combined therapy with the above methods, may lead to premature ovarian… read more here.
Keywords: endocrine function; medicine; oncofertility bench; bench bedside ... See more keywords
50 Years From Bench to Bedside: His Bundle Pacing Versus Right Ventricular Apical Pacing.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.04.094
Abstract: Abdelrahman et al. [(1)][1] reported the clinical results of a comparative study in patients receiving permanent His bundle pacing with those implanted with right ventricular pacemakers. They were able to achieve permanent His bundle pacing in… read more here.
Keywords: right ventricular; bundle pacing; bench bedside; years bench ... See more keywords
Translation of pulmonary protein therapy from bench to bedside: Addressing the bioavailability challenges
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102664
Abstract: Abstract Protein-based therapeutics are significantly reaching the market owing to strides in genetic engineering and target specific drug design. However, majority of the products are available as parenteral and subcutaneous dosage forms. The lungs provide… read more here.
Keywords: pulmonary protein; bench bedside; translation pulmonary; degradation ... See more keywords
Monitoring autophagy in cancer: from bench to bedside.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2019.05.016
Abstract: Autophagy refers to an essential mechanism that evolved to sustain eukaryotic homeostasis and metabolism during instances of nutrient deprivation. During autophagy, intracellular cargo is encapsulated and delivered to the lysosome for elimination. Loss of basal… read more here.
Keywords: cancer bench; autophagy cancer; monitoring autophagy; biology ... See more keywords
Switching between P2Y12 antagonists - From bench to bedside.
Sign Up to like & getrecommendations! Published in 2019 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2019.01.003
Abstract: Platelet P2Y12 receptors play a key role in platelet activation and thrombus formation. Accordingly, P2Y12 receptor antagonists are the cornerstone of secondary prevention of atherothrombotic events in patients undergoing percutaneous coronary intervention (PCI). The availability… read more here.
Keywords: p2y12 antagonists; antagonists bench; pharmacology; bench bedside ... See more keywords
From bench to bedside: A narrative review and institutional experience with experimental models for vascular device design and translation.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in vascular surgery"
DOI: 10.1053/j.semvascsurg.2022.09.005
Abstract: The past 2 decades have seen a rise in vascular innovations and a rapid evolution in endovascular device technology, with the emergence of atherectomy, intravascular lithotripsy, drug elution technology, thrombectomy devices, and many more. Like… read more here.
Keywords: narrative review; bench bedside; review institutional; design ... See more keywords
Development of new levodopa treatment strategies in Parkinson’s disease—from bedside to bench to bedside
Sign Up to like & getrecommendations! Published in 2017 at "Upsala Journal of Medical Sciences"
DOI: 10.1080/03009734.2017.1285374
Abstract: Abstract This review will illustrate the process of moving from an idea through preclinical research and Galenic developments into clinical investigations and finally to approval by regulatory agencies within the European Union. The two new… read more here.
Keywords: bedside; treatment strategies; bench bedside; bedside bench ... See more keywords
Anticalin® proteins: from bench to bedside
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2021.1839046
Abstract: ABSTRACT Introduction Anticalin proteins are engineered versions of lipocalins that constitute a novel class of clinical-stage biopharmaceuticals. The lipocalins exhibit a central β-barrel with eight antiparallel β-strands and an α-helix attached to its side. Four… read more here.
Keywords: anticalin proteins; bench bedside; proteins bench; oncology ... See more keywords