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Published in 2020 at "Genome Biology"
DOI: 10.1186/s13059-020-01972-x
Abstract: Genome-wide pooled CRISPR-Cas-mediated knockout, activation, and repression screens are powerful tools for functional genomic investigations. Despite their increasing importance, there is currently little guidance on how to design and analyze CRISPR-pooled screens. Here, we provide…
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Keywords:
benchmark algorithms;
analysis pooled;
pooled crispr;
crispr screens ... See more keywords