Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) and myelodysplastic syndrome with ring sideroblasts (MDS‐RS)
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26182
Abstract: REFERENCES 1. Kumar SK, Callander NS, Hillengass J, et al. NCCN guidelines insights: multiple myeloma, version 1.2020. J Natl Compr Canc Netw. 2019;17 (10):1154-1165. 2. Cheson BD, Leoni L. Bendamustine: mechanism of action and clinical… read more here.
Keywords: genomic transcriptomic; ring sideroblasts; multiple myeloma; myelodysplastic syndrome ... See more keywords
Phase 1 Study Evaluating Pharmacokinetics and Tolerability of Ofatumumab Combined With Bendamustine in Patients With Indolent B‐Cell Non‐Hodgkin's Lymphoma
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DOI: 10.1002/cpdd.1133
Abstract: The pharmacokinetics (PK) and safety of ofatumumab and bendamustine alone and in combination were evaluated in patients with treatment‐naive or relapsed indolent B‐cell non‐Hodgkin lymphoma (iNHL). Patients were randomly assigned to ofatumumab and bendamustine or… read more here.
Keywords: hodgkin lymphoma; non hodgkin; indolent cell; concentration ... See more keywords
Brentuxinmab vedotin, alone or combine with bendamustine in the treatment of natural killer T cell lymphoma
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DOI: 10.1002/hon.3042
Abstract: Natural killer (NK)/T cell lymphoma is a highly aggressive subtype of non‐Hodgkin lymphoma. The prognosis of patients with natural killer T cell lymphoma (NKTCL) remains poor. More potent treatment strategies are urgently needed to improve… read more here.
Keywords: cell; cell lymphoma; natural killer; bendamustine ... See more keywords
Polatuzumab vedotin combined with rituximab-bendamustine immediately before stem cell mobilization in relapsed diffuse large B-cell lymphoma
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DOI: 10.1007/s00277-022-04803-0
Abstract: Dear Editor, We have read with great interest the report by Wang et al. [1] regarding autologous hematopoietic stem cell transplantation (ASCT) following polatuzumab vedotin combined with rituximab-bendamustine (Pola-BR) for relapsed diffuse large B-cell lymphoma… read more here.
Keywords: bendamustine; therapy; pola; cell ... See more keywords
Simultaneous determination of bendamustine and γ-hydroxybendamustine in mice dried blood spots and its application in a mice pharmacokinetic study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.05.052
Abstract: A selective, sensitive and rapid mice dried blood spot (DBS) method has been developed and validated for the simultaneous quantification of bendamustine (BM) and γ-hydroxy-bendamustine (HBM) as per regulatory guidelines using an LC-MS/MS. Quality control,… read more here.
Keywords: study; dried blood; mice dried; pharmacokinetic study ... See more keywords
Serum immunoglobulin G as a discriminator of infection in follicular lymphoma patients undergoing chemotherapy with bendamustine in combination with rituximab.
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DOI: 10.1080/16078454.2022.2051863
Abstract: OBJECTIVES Chemotherapy, including bendamustine, usually causes lymphocytopaenia and hypogammaglobulinaemia as side effects in patients with haematological malignancies. Therefore, the possibility has been considered that these immunological adverse events induced by bendamustine may lead to infectious… read more here.
Keywords: patients undergoing; follicular lymphoma; bendamustine; rituximab ... See more keywords
Brentuximab vedotin in association with bendamustine in refractory or multiple relapsed Hodgkin lymphoma. A retrospective real‐world study
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DOI: 10.1111/ejh.13400
Abstract: In order to assess the efficacy of brentuximab vedotin (Bv) in combination with bendamustine (B) in multiple relapsed or refractory (RR) classic Hodgkin lymphoma (cHL), medical records of 47 patients treated with BvB in second… read more here.
Keywords: brentuximab vedotin; multiple relapsed; hodgkin lymphoma; bendamustine ... See more keywords
Successful use of cytarabine and bendamustine in a patient with mantle cell lymphoma and acute renal failure using intermittent hemodialysis: A case report
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DOI: 10.1177/1078155217754244
Abstract: Mantle cell lymphoma is a mature B-cell non-Hodgkin lymphoma characterized by the hallmark (11;14) chromosomal translocation, which often presents with lymphadenopathy and extra-nodal involvement. Young, fit patients are generally treated with chemotherapy approaches that incorporate… read more here.
Keywords: cytarabine; mantle cell; cell; bendamustine ... See more keywords
Bendamustine-induced nephrogenic diabetes insipidus – A case report
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DOI: 10.1177/10781552211013878
Abstract: Introduction In patients with relapsed or refractory lymphoma, high-dose chemoimmunotherapy with subsequent autologous hematopoietic cell transplantation (HCT) is a standard of care. Bendamustine, an alkylating agent, is used in the BeEAM (bendamustine, etoposide, cytarabine, melphalan)… read more here.
Keywords: diabetes insipidus; case report; bendamustine; bendamustine induced ... See more keywords
Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial.
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DOI: 10.1182/blood-2017-04-778175
Abstract: Primary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a bone marrow clonal B-cell lymphoproliferation results in autoimmune hemolytic anemia and cold-induced circulatory symptoms. Rituximab monotherapy and fludarabine-rituximab in combination are… read more here.
Keywords: rituximab; chronic cold; trial; cold agglutinin ... See more keywords
Bendamustine-Rituximab Does Not Improve Survival over Rituximab Monotherapy for Older Patients with Nodal or Splenic Marginal Zone Lymphoma
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DOI: 10.1182/blood-2019-121841
Abstract: Background: Nodal and splenic marginal zone lymphomas (NMZL/SMZL) are rare, usually disseminated, and typically diagnosed in older patients (median age 69 years). They are increasingly treated with first-line bendamustine/rituximab (BR) based on phase 3 trials… read more here.
Keywords: rituximab; line; nmzl smzl; bendamustine ... See more keywords