Protein Flexibility and Synergy of HMG Domains Underlie U-Turn Bending of DNA by TFAM in Solution.
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DOI: 10.1016/j.bpj.2017.11.3743
Abstract: Human mitochondrial transcription factor A (TFAM) distorts DNA into a U-turn, as shown by crystallographic studies. The relevance of this U-turn is associated with transcription initiation at the mitochondrial light strand promoter (LSP). However, it… read more here.
Keywords: protein; dna; tfam; solution ... See more keywords