Transcriptomic evidence for tumor-specific beneficial or adverse effects of TGFβ pathway inhibition on the prognosis of patients with liver cancer.
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DOI: 10.1002/2211-5463.13647
Abstract: Therapeutic targeting of the Transforming Growth Factor beta (TGFβ) pathway in cancer represents a clinical challenge since TGFβ exhibits either tumor suppressive or tumor promoting properties, depending on the tumor stage. Thus, treatment with galunisertib,… read more here.
Keywords: galunisertib; beneficial adverse; tgf pathway; tumor ... See more keywords