Senescent T cells: Beneficial and detrimental roles.
Sign Up to like & getrecommendations! Published in 2023 at "Immunological reviews"
DOI: 10.1111/imr.13206
Abstract: As the thymus involutes during aging, the T-cell pool has to be maintained by the periodic expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of activation and proliferation drive the… read more here.
Keywords: immunopathology; senescent cells; detrimental roles; cells beneficial ... See more keywords
A Janus-Faced Bacterium: Host-Beneficial and -Detrimental Roles of Cutibacterium acnes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.673845
Abstract: The bacterial species Cutibacterium acnes (formerly known as Propionibacterium acnes) is tightly associated with humans. It is the dominant bacterium in sebaceous regions of the human skin, where it preferentially colonizes the pilosebaceous unit. Multiple… read more here.
Keywords: bacterium; beneficial detrimental; janus faced; faced bacterium ... See more keywords
Beneficial and Detrimental Roles of Heme Oxygenase-1 in the Neurovascular System
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137041
Abstract: Heme oxygenase (HO) has both beneficial and detrimental effects via its metabolites, including carbon monoxide (CO), biliverdin or bilirubin, and ferrous iron. HO-1 is an inducible form of HO that is upregulated by oxidative stress,… read more here.
Keywords: oxygenase neurovascular; neurovascular system; heme oxygenase; roles heme ... See more keywords
Senescence of Tumor Cells in Anticancer Therapy—Beneficial and Detrimental Effects
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911082
Abstract: Cellular senescence process results in stable cell cycle arrest, which prevents cell proliferation. It can be induced by a variety of stimuli including metabolic stress, DNA damage, telomeres shortening, and oncogenes activation. Senescence is generally… read more here.
Keywords: tumor cells; senescence tumor; senescence; beneficial detrimental ... See more keywords