Development and First Use of the Patient’s Qualitative Assessment of Treatment (PQAT) Questionnaire in Type 2 Diabetes Mellitus to Explore Individualised Benefit–Harm of Drugs Received During Clinical Studies
Sign Up to like & getrecommendations! Published in 2019 at "Drug Safety"
DOI: 10.1007/s40264-019-00877-4
Abstract: Introduction Individualised benefit–harm assessments can help identify patient-perceived benefits and harms of a treatment, and associated trade-offs that may influence patients’ willingness to use a treatment. This research presents the first use of a patient-reported… read more here.
Keywords: pqat; benefit harm; treatment; use patient ... See more keywords
Renal Outcomes and the Relative Benefit and Harm of Intensive Treatment of Hypertension.
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DOI: 10.1016/j.jacc.2018.04.090
Abstract: We read with interest the paper by Philips et al. [(1)][1] reporting the effect of baseline 10-year cardiovascular disease risk on primary outcome events and all-cause serious adverse events in SPRINT (Systolic Blood Pressure Intervention Trial).… read more here.
Keywords: benefit harm; renal outcomes; intensive treatment; outcomes relative ... See more keywords
Benefit–harm analysis of azithromycin for the prevention of acute exacerbations of chronic obstructive pulmonary disease
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DOI: 10.1136/thoraxjnl-2021-217962
Abstract: Background Low-dose oral azithromycin therapy is recommended as a preventive treatment for acute exacerbations of COPD. However, the overall benefit–harm balance of this treatment has not been well studied. Methods A probabilistic Markov model of… read more here.
Keywords: acute exacerbations; benefit; benefit harm; analysis ... See more keywords
Rejoinder to Dr Vickers
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DOI: 10.1177/17407745211068548
Abstract: We thank Dr Vickers for his thoughtful commentary. Dr Vickers argues that if a benefit–harm metric includes absolutely every aspect of the decision, then there is no clinically relevant difference, and even for the smallest… read more here.
Keywords: benefit harm; net benefit; evidence; benefit ... See more keywords