Methylation markers differentiate thyroid cancer from benign nodules
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0702-2
Abstract: PurposeThe incidence of thyroid cancer (TC) is increasing. Cytology by itself cannot distinguish TC from some benign nodules especially in certain subtypes of TC. Our immediate goal is to identify DNA methylation markers for early… read more here.
Keywords: sensitivity; methylation; benign nodules; thyroid cancer ... See more keywords
Assessment of Plasma Proteomics Biomarker’s Ability to Distinguish Benign From Malignant Lung Nodules
Sign Up to like & getrecommendations! Published in 2018 at "Chest"
DOI: 10.1016/j.chest.2018.02.012
Abstract: BACKGROUND: Lung nodules are a diagnostic challenge, with an estimated yearly incidence of 1.6 million in the United States. This study evaluated the accuracy of an integrated proteomic classifier in identifying benign nodules in patients… read more here.
Keywords: lung; lung nodules; integrated classifier; benign nodules ... See more keywords
The genetic landscape of benign thyroid nodules revealed by whole exome and transcriptome sequencing
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15533
Abstract: The genomic alterations for benign thyroid nodule, especially adenomatoid nodule, one of the most common types of hyperplasia lesion, are ill-studied. Here, we show whole-exome sequencing and/or transcriptome sequencing data on adenomatoid nodules with or… read more here.
Keywords: benign; transcriptome sequencing; benign thyroid; whole exome ... See more keywords
Malignancy risk estimation of pulmonary nodules in screening CTs: Comparison between a computer model and human observers
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DOI: 10.1371/journal.pone.0185032
Abstract: Purpose To compare human observers to a mathematically derived computer model for differentiation between malignant and benign pulmonary nodules detected on baseline screening computed tomography (CT) scans. Methods A case-cohort study design was chosen. The… read more here.
Keywords: human observers; risk; computer; benign nodules ... See more keywords