Microwave-assisted synthesis of pharmacologically active 4-phenoxyquinolines and their benzazole-quinoline hybrids through SNAr reaction of 4,7-dichloroquinoline and phenols using [bmim][PF6] as a green solvent.
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DOI: 10.2174/1570179419666220830090614
Abstract: BACKGROUND Quinoline and its derivatives have been shown to display a wide spectrum of biological properties, especially anticancer activity. Particularly, diverse potent anticancer drugs are based on the 4-phenoxyquinoline skeleton, acting as small-molecules VEGR2 and/or… read more here.
Keywords: reaction; bmim pf6; synthesis; benzazole quinoline ... See more keywords