Synthesis of benzene derivatives with multiple PCl2 groups.
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DOI: 10.1002/cplu.202300072
Abstract: The chlorination of 1,2-diphosphinobenzene with PCl5 to 1,2-bis(dichlorophosphino)benzene (2) was performed with high yields (93%) despite the high number of P-H functions. The method was further applied to other phosphanes, enabling the first synthesis and… read more here.
Keywords: benzene; dichlorophosphino benzene; multiple pcl2; derivatives multiple ... See more keywords
Dearomatization [4+2] Cycloaddition of Nonactivated Benzene Derivatives.
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DOI: 10.1021/acs.orglett.2c01630
Abstract: Dearomatization reactions have recently emerged as a powerful tool for the rapid buildup of molecular complexity. Here, an unparalleled thermal dearomatization [4+2] cycloaddition reaction between benzene derivatives and a 2H-phosphindole tungsten complex was reported. The… read more here.
Keywords: dearomatization cycloaddition; dearomatization; cycloaddition nonactivated; nonactivated benzene ... See more keywords
Development of reliable quantitative structure–toxicity relationship models for toxicity prediction of benzene derivatives using semiempirical descriptors
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2022.2118092
Abstract: Abstract The Health and environmental hazards of benzene and nitrobenzene (NB) derivatives have remained a topic of interest of researchers. In silico methods for prediction of toxicity of chemicals have proved their worth in accurate… read more here.
Keywords: quantitative structure; toxicity; toxicity relationship; benzene derivatives ... See more keywords
Friedel–Crafts acylation of benzene derivatives in tunable aryl alkyl ionic liquids (TAAILs)
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DOI: 10.3762/bjoc.19.20
Abstract: An iron(III) chloride hexahydrate-catalyzed Friedel–Crafts acylation of benzene derivatives in tunable aryl alkyl ionic liquids (TAAILs) has been developed. Through optimization of the metal salt, reaction conditions and ionic liquids, we were able to design… read more here.
Keywords: derivatives tunable; acylation benzene; friedel crafts; ionic liquids ... See more keywords