Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-17432-3
Abstract: Benzene is an occupational and environmental toxicant, causing hematopoietic damage. Our study is aimed to extract the trend of benzene-induced leukemia (BIL) and qualitatively and quantitatively estimate research on it. Publications on BIL were identified… read more here.
Keywords: benzene induced; research; benzene; induced leukemia ... See more keywords
LincRNA-p21 promotes p21-mediated cell cycle arrest in benzene-induced hematotoxicity by sponging miRNA-17-5p.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.118706
Abstract: Benzene is widely employed in manufacturing and causes hematotoxic effects and leukemia in humans. A long intergenic noncoding RNA (lincRNA)-microRNA (miRNA)-mRNA coexpression and competing endogenous RNA (ceRNA) regulatory network was constructed by bioinformatics analysis based… read more here.
Keywords: benzene induced; p21; cell; hematotoxicity ... See more keywords
Acetyl-l-carnitine partially prevents benzene-induced hematotoxicity and oxidative stress in C3H/He mice.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.02.013
Abstract: Benzene is an environmental pollutant and occupational toxicant which induces hematotoxicity. Our previous metabonomics study suggested that acetyl-l-carnitine (ALCAR) decreased in the mouse plasma and bone marrow (BM) cells due to benzene exposure. In the… read more here.
Keywords: acetyl carnitine; benzene induced; c3h mice; alcar ... See more keywords
The effects of Nrf2 knockout on regulation of benzene‐induced mouse hematotoxicity
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DOI: 10.1016/j.taap.2018.09.002
Abstract: ABSTRACT Previous studies have demonstrated that oxidative stress is implicated in benzene‐induced hematotoxicity. However, the low dose‐response effects and the mechanism underlying perturbation of hematopoiesis remain to be defined. This study aims to address the… read more here.
Keywords: benzene induced; benzene; regulation benzene; induced hematotoxicity ... See more keywords
Benzene induces haematotoxicity by promoting deacetylation and autophagy
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DOI: 10.1111/jcmm.14003
Abstract: Chronic exposure to benzene is known to be associated with haematotoxicity and the development of aplastic anaemia and leukaemia. However, the mechanism underlying benzene‐induced haematotoxicity, especially at low concentrations of chronic benzene exposure has not… read more here.
Keywords: benzene induced; haematotoxicity; autophagy; benzene induces ... See more keywords
Plasma metabolomics study reveals the critical metabolic signatures for benzene-induced hematotoxicity
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.154999
Abstract: Metabolomics has been used to explore the molecular mechanism and screen biomarkers. However, the critical metabolic signatures associated with benzene-induced hematotoxicity remain elusive. Here, we performed a plasma metabolomics study in 86 benzene-exposed workers and… read more here.
Keywords: benzene induced; critical metabolic; induced hematotoxicity; metabolic signatures ... See more keywords