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Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c00047
Abstract: We report the first enantioselective total syntheses of the hasubanan alkaloid (-)-metaphanine and the norhasubanan alkaloid (+)-stephadiamine. Key features of these syntheses include diastereoselective oxidative phenolic coupling reaction and subsequent regioselective intramolecular aza-Michael reaction, which…
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Keywords:
benzilic acid;
type rearrangement;
aza benzilic;
enantioselective total ... See more keywords
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Published in 2019 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2019.00554.7
Abstract: SIRT3 is one of the major mitochondrial deacetylase and has been shown to regulate the activity of many mitochondrial proteins. The sirt3 gene is observed in various human cancers. Sirutin gene family is hypothesized to…
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Keywords:
docking analysis;
benzilic acid;
active site;
protein ... See more keywords