Synthesis of benzimidazole based hydrazones as non-sugar based α-glucosidase inhibitors: Structure activity relation and molecular docking.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21807
Abstract: In search for α-glucosidase inhibitors used in the treatment of diabetes mellitus, a series of unique benzimidazole based hydrazones derivatives were synthesized (5a-5p), which were then investigated for their in vitro α-glucosidase inhibitory potential. The… read more here.
Keywords: benzimidazole based; glucosidase inhibitors; based hydrazones; structure ... See more keywords
Conventional and microwave-assisted synthesis of new indole-tethered benzimidazole-based 1,2,3-triazoles and evaluation of their antimycobacterial, antioxidant and antimicrobial activities
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Diversity"
DOI: 10.1007/s11030-018-9828-1
Abstract: A new series of triheterocycles containing indole–benzimidazole-based 1,2,3-triazole hybrids have been synthesized in good yields via a microwave-assisted click reaction. All the compounds were characterized by IR, $$^{1}\hbox {H}$$1H NMR, $$^{13}\hbox {C}$$13C NMR and mass… read more here.
Keywords: hbox hbox; benzimidazole based; upmu hbox; microwave assisted ... See more keywords
Benzimidazole-based hyper-cross-linked polymers for effective adsorption of chlortetracycline from aqueous solution
Sign Up to like & getrecommendations! Published in 2020 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2020.104562
Abstract: Abstract In this study, benzimidazole-based hyper-cross-linked polymers (HCPs) with hierarchical pores were synthesized through facile one-step Friedel-Crafts reaction and applied to the adsorption of chlortetracycline from aqueous solution. The mole ratio of benzene to benzimidazole… read more here.
Keywords: adsorption; hyper cross; benzimidazole based; based hyper ... See more keywords
A Novel Benzimidazole-Based Fluorescence Probe for Detecting Zinc Ion in Aqueous Solution and Zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1246/bcsj.20180390
Abstract: A novel selective and sensitive chemosensor, (E)-1-((((1H-benzo[d]imidazol-2-yl)methyl)imino)methyl)naphthalen-2-ol (BIN), was developed for fluorescence detection of Zn2+. The compound BIN acts as... read more here.
Keywords: probe detecting; benzimidazole based; fluorescence; novel benzimidazole ... See more keywords
Novel benzimidazole-based conjugated polyelectrolytes: synthesis, solution photophysics and fluorescent sensing of metal ions
Sign Up to like & getrecommendations! Published in 2020 at "e-Polymers"
DOI: 10.1515/epoly-2020-0003
Abstract: Abstract Two benzimidazole-based conjugated polyelectrolytes (+)-PPBIPV and (-)-PPBIPV which have opposite charges on their side chains were synthesized via Heck coupling reaction and characterized by 1H-NMR, UV-vis and PL spectroscopy. These two polyelectrolytes are both… read more here.
Keywords: benzimidazole based; metal ions; conjugated polyelectrolytes; solution ... See more keywords
Electrospun Benzimidazole-Based Polyimide Membrane for Supercapacitor Applications
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12100961
Abstract: A benzimidazole-containing diamine monomer was prepared via a simple one-step synthesis process. A two-step procedure involving polycondensation in the presence of aromatic dianhydrides (4,4′-oxydiphthalic anhydride, ODPA) followed by thermal imidization was then performed to prepare… read more here.
Keywords: based polyimide; benzimidazole based; supercapacitor applications; capacitance ... See more keywords
Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27186087
Abstract: Twenty-four analogues of benzimidazole-based thiazoles (1–24) were synthesized and assessed for their in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory potential. All analogues were found to exhibit good inhibitory potential against cholinesterase enzymes, having IC50… read more here.
Keywords: molecular docking; benzimidazole based; cholinesterase inhibitors; multipotent cholinesterase ... See more keywords
Screening of Benzimidazole-Based Anthelmintics and Their Enantiomers as Repurposed Drug Candidates in Cancer Therapy
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DOI: 10.3390/ph14040372
Abstract: Repurposing of approved non-antitumor drugs represents a promising and affordable strategy that may help to increase the repertoire of effective anticancer drugs. Benzimidazole-based anthelmintics are antiparasitic drugs commonly employed both in human and veterinary medicine.… read more here.
Keywords: benzimidazole based; drug; cancer therapy; cancer ... See more keywords