Synthesis of benzimidazole-linked-1,3,4-oxadiazole carboxamides as GSK-3β inhibitors with in vivo antidepressant activity.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.01.040
Abstract: Recent findings of potential implications of glycogen synthase kinase-3β (GSK-3β) dysfunction in psychiatric disorders like depression, have increased focus for development of GSK-3β inhibitors with possible anti-depressant activity. Keeping this in view, we synthesized a… read more here.
Keywords: oxadiazole carboxamides; linked oxadiazole; benzimidazole linked; vivo antidepressant ... See more keywords
Incorporation of benzimidazole linked polymers into Matrimid to yield mixed matrix membranes with enhanced CO2/N2 selectivity
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Membrane Science"
DOI: 10.1016/j.memsci.2018.02.054
Abstract: Abstract Two different highly cross-linked benzimidazole linked polymers (BILPs) displaying high surface area were successfully incorporated into Matrimid polymer to form a series of new mixed matrix membranes (MMMs). The surface functionality of the BILPs,… read more here.
Keywords: benzimidazole linked; linked polymers; matrix; gas ... See more keywords
α-Amino Acid Derived Benzimidazole-Linked Rhodamines: A Case of Substitution Effect at the Amino Acid Site toward Spiro Ring Opening for Selective Sensing of Al3+ Ions.
Sign Up to like & getrecommendations! Published in 2017 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.7b00835
Abstract: α-Amino acid derived benzimidazole-linked rhodamines have been synthesized, and their metal ion sensing properties have been evaluated. Experimentally, l-valine- and l-phenylglycine-derived benzimidazole-based rhodamines 1 and 2 selectively recognize Al3+ ion in aqueous CH3CN (CH3CN/H2O 4/1… read more here.
Keywords: derived benzimidazole; benzimidazole linked; acid derived; amino acid ... See more keywords
A one-pot synthetic approach for the construction of a thiazolo[3,2-a]benzimidazole-linked quinazoline scaffold via palladium-catalyzed reactions
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00751e
Abstract: 4-(2-Substituted-[1,3]thiazolo[3,2-a]benzimidazol-3-yl)quinazolin-2-amines were prepared by the multi-component reaction of 2,4-dichloroquinazoline, terminal alkynes, secondary amines, and 1H-benzo[d]imidazole-2(3H)-thione in the presence of a palladium–copper catalyst. This one-pot process provided an efficient and successful approach for the synthesis of… read more here.
Keywords: thiazolo benzimidazole; linked quinazoline; benzimidazole linked; one pot ... See more keywords