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Published in 2018 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201800029
Abstract: meta‐Cyanobenzyl‐substituted N‐heterocyclic carbene (NHC) precursors were synthesized by the reaction of a series of N‐(alkyl)benzimidazolium with 3‐bromomethyl‐benzonitrile. These benzimidazolium salts were characterized by using 1H NMR, 13C NMR, FTIR spectroscopy, and elemental analysis techniques. The…
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Keywords:
carbonic anhydrase;
meta cyanobenzyl;
benzimidazolium salts;
benzimidazolium ... See more keywords
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Published in 2017 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-017-2995-3
Abstract: This article describes synthesis of N-morpholinoethylbenzimidazole (1), 2-morpholinoethyl-substituted benzimidazolium salts (NHC precursors, 2a–c), and their Ag(I) N-heterocyclic carbene (NHC) complexes (3a–c). All compounds were characterized by 1H and 13C Nuclear Magnetic Resonance (NMR), Fourier Transform…
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Keywords:
benzimidazolium salts;
morpholinoethyl substituted;
substituted benzimidazolium;
heterocyclic carbene ... See more keywords
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Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03630
Abstract: An intramolecular sp3 C-H amination reaction of aniline derivatives has been established. This reaction employs molecular iodine (I2) under transition-metal-free conditions and produces 1,2-fused or 1,2-disubstituted benzimidazoles. This operationally simple synthetic process works well with…
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Keywords:
disubstituted benzimidazoles;
sp3 amination;
fused disubstituted;
benzimidazoles benzimidazolium ... See more keywords