Design, synthesis, and antidepressant/anticonvulsant activities of 3H-benzo[f]chromen chalcone derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-021-02742-5
Abstract: In this study, 19 3H-benzo[f]chromen chalcone derivatives (2a–2s) were obtained from 2-hydroxy-1-naphthaldehyde as the starting material, and their structures were confirmed by IR, 1H NMR, 13C NMR, and ESI-MS analyses. The antidepressant activities of the… read more here.
Keywords: chromen chalcone; design synthesis; activity; benzo chromen ... See more keywords
(E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173137
Abstract: The current study was aimed to assess the protective effect of a new molecule (E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide, denoted 1c, against cardiac remodeling process in isoproterenol (Isop) induced myocardial infarction (MI) in rats. Male Wistar rats were randomly… read more here.
Keywords: chromen ethylidene; ethylidene benzohydrazide; vivo; benzo chromen ... See more keywords
Investigation of the Fluorescence Turn-off Mechanism, Genome, Molecular Docking In Silico and In Vitro Studies of 2-Acetyl-3H-benzo[f]chromen-3-one
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DOI: 10.1021/acsomega.2c02424
Abstract: The present study harnesses fluorescence quenching between a nonfluorescent aniline and fluorophore 2-acetyl-3H-benzo[f]chromen-3-one [2AHBC] in binary solvent mixtures of acetonitrile and 1,4-dioxane at room temperature and explores the fluorophore as an antimicrobial material. Our findings… read more here.
Keywords: fluorescence turn; chromen one; benzo chromen; investigation fluorescence ... See more keywords
Oxidant-free, three-component synthesis of 7-amino-6H-benzo[c]chromen-6-ones under green conditions
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DOI: 10.1039/c9ra07108c
Abstract: Three-component synthesis of 7-amino-6H-benzo[c]chromen-6-ones was achieved under oxidant-free green conditions. read more here.
Keywords: amino benzo; benzo chromen; component synthesis; synthesis amino ... See more keywords
Efficient Synthesis of 7,8-Dihydro-6H-benzo[c]chromen-6-one Derivatives by Base-Mediated Chemoselective Annulation of Alkylidene Malononitriles with α,β-Unsaturated Coumarins
Sign Up to like & getrecommendations! Published in 2021 at "Synlett"
DOI: 10.1055/s-0040-1706012
Abstract: An efficient and chemoselective synthesis of biologically valuable 7,8-dihydro-6H-benzo[c]chromen-6-ones is described. In this method, neither a metal catalyst nor expensive starting materials are needed, and the products can be purified by simple filtration and washing… read more here.
Keywords: benzo chromen; dihydro benzo; efficient synthesis;
Design, Synthesis, and Biological Evaluation of Novel 6H-Benzo[c]chromen-6-one Derivatives as Potential Phosphodiesterase II Inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22115680
Abstract: Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. As part of this research, a series of alkoxylated… read more here.
Keywords: design synthesis; biological evaluation; benzo chromen; one derivatives ... See more keywords