Synthesis of tricyclic and tetracyclic benzo[6,7]cycloheptane derivatives linked morpholine moiety as CDK2 inhibitors.
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DOI: 10.1002/ddr.22074
Abstract: With the aim of developing cyclin-dependent kinase 2 (CDK2) inhibitors with strong antibreast cancer efficacy, new tricyclic and tetracyclic benzo[6,7]cycloheptane derivatives were synthesized. The newly synthesized tri- and tetracyclic derivatives were achieved from the reaction… read more here.
Keywords: cycloheptane derivatives; tricyclic tetracyclic; tetracyclic benzo; benzo cycloheptane ... See more keywords