Benzo[d][1,3]Oxazine‐Assisted C─H Annulation of Arenes with Diarylacetylenes: Access to 3,4‐diarylisoquinolinones
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500225
Abstract: A novel Rh(III)‐catalyzed [4 + 2] annulation of diarylacetylenes with 2‐aryl‐4H‐benzo[d][1,3]oxazines is described to produce a new class of 3,4‐diarylisoquinolinones through a ring‐opening C─H annulation of benzo[d][1,3]oxazine moiety. This is the first report on C─H functionalazation of… read more here.
Keywords: annulation; oxazine assisted; benzo oxazine; assisted annulation ... See more keywords
Catalyst- and Additive-Free Approach to Constructing Benzo-oxazine, Benzo-oxazepine, and Benzo-oxazocine: O Atom Transfer and C═O, C-N, and C-O Bond Formation at Room Temperature.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c02895
Abstract: An exclusive synthesis of benzo-oxazine, benzo-oxazepine, and benzo-oxazocine from aryl propanal and 2-(hydroxyamino)phenyl alcohol under metal-free conditions is described. O atom transfer and formation of new C═O, C-N, and C-O bonds occur at room temperature… read more here.
Keywords: benzo oxazepine; benzo; oxazine benzo; oxazepine benzo ... See more keywords
Bio-computational modeling, POM analysis and molecular dynamic simulation for novel synthetic quinolone and benzo[d][1,3]oxazine candidates as antimicrobial inhibitors
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DOI: 10.1038/s41598-024-73972-x
Abstract: The current study offers a metal-free, direct, and successful synthesis technique for a new series of quinolinone and benzo[d][1,3]oxazine, along with an assessment of their biological activities. Heteroannulation of anthranilic acid with carbonyl-containing chemicals (aroyl… read more here.
Keywords: benzo oxazine; oxazine candidates; quinolone benzo; oxazine ... See more keywords
Investigation for the easy and efficient synthesis of 1H-benzo[d][1,3]oxazine-2,4-diones
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DOI: 10.1039/d5ra04014k
Abstract: We investigated a two-step approach for the easy and efficient synthesis of 1H-benzo[d][1,3]oxazine-2,4-diones starting from 2-aminobenzoic acids, using the urethane type fluorenylmethyloxycarbonyl (Fmoc), benzyloxycarbonyl (Cbz) and ethyloxycarbonyl (EtOCO) groups as the source of carbonyloxy group,… read more here.
Keywords: benzo oxazine; oxazine diones; efficient synthesis; easy efficient ... See more keywords