Three-Component One-Pot Construction of 2-Aryl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidines Using Solid Calcium Carbide as a Surrogate of Gaseous Acetylene.
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DOI: 10.1021/acs.orglett.2c02331
Abstract: A concise method for the construction of 2-aryl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidines using solid calcium carbide instead of gaseous acetylene as an alkyne source and 2-aminobenzothiazoles and aromatic aldehydes as substrates through one-pot three-component cascade reactions is described. The… read more here.
Keywords: using solid; aryl benzo; benzo thiazolo; pyrimidines using ... See more keywords
The ChCl/HGA-based DES as a capable and new catalyst for the green synthesis of benzo[4,5]thiazolo[3,2-a]chromeno[4,3-d]pyrimidin-6-one
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DOI: 10.1038/s41598-025-90953-w
Abstract: A novel deep eutectic solvent (ChCl/HGA-DES) was prepared by a mixture of two moles of choline chloride (ChCl) and one mole of 2,3-dihydroxybenzoic acid (hypogallic acid, HGA). The eutectic point phase diagram showed that the… read more here.
Keywords: chcl hga; benzo thiazolo; hga;
Crystal structure of 1-amino-3-(4-chlorophenyl)-2-cyano-3H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carboxamide
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DOI: 10.1107/s2056989025001562
Abstract: The tricyclic ring system of the title compound departs from planarity in the region of the sp3 carbon atom. The three-dimensional packing involves four classical hydrogen bonds and one N⋯Cl halogen bond. read more here.
Keywords: chlorophenyl cyano; crystal structure; benzo thiazolo; amino chlorophenyl ... See more keywords
Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazole Derivatives via C-H Bond Functionalization of Disulfide Intermediates
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DOI: 10.3390/molecules27051464
Abstract: Many nitrogen- and sulfur-containing heterocyclic compounds exhibit biological activity. Among these heterocycles are benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles for which two main synthetic approaches exist. Here we report a new synthetic protocol that allows the preparation of these tricyclic… read more here.
Keywords: benzo thiazolo; bond functionalization; synthesis benzo; thiazolo triazole ... See more keywords