Synthesis of 3-(Methylsulfonyl)benzo[ b]thiophenes from Methyl(2-alkynylphenyl)sulfanes and Sodium Metabisulfite via a Radical Relay Strategy.
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DOI: 10.1021/acs.orglett.9b00100
Abstract: A radical relay strategy for the generation of 3-(methylsulfonyl)benzo[ b]thiophenes through a reaction of methyl(2-alkynylphenyl)sulfanes with sodium metabisulfite in the presence of a photocatalyst under visible light irradiation is developed. This photoinduced sulfonylation proceeds efficiently… read more here.
Keywords: relay; radical relay; sodium; relay strategy ... See more keywords
One-step synthesis of benzo[b]thiophenes by aryne reaction with alkynyl sulfides†
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DOI: 10.1039/d0sc04450d
Abstract: An aryne reaction with alkynyl sulfides affording benzo[b]thiophenes is disclosed. A wide range of 3-substituted benzothiophenes were synthesized from easily available o-silylaryl triflates and alkynyl sulfides in a one-step intermolecular manner. The synthesis of diverse… read more here.
Keywords: aryne reaction; alkynyl sulfides; one step; reaction alkynyl ... See more keywords
Cobalt-Mediated [2+2+2] Cycloadditions of Alkynes to Benzo-[b]furans and Benzo[b]thiophenes: A Potential Route toward Morphanoids
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DOI: 10.1055/s-0036-1589147
Abstract: Exploratory studies of the CpCo-mediated [2+2+2] cycloaddition of alkynes to the 2,3-double bond of benzo[b]furans (and some benzo[b]thiophenes) are presented, with the general aim to access morphinan substructures. The basic feasibility of constructing Co-complexed tetrahydrophenanthro[4,5-bcd]furans… read more here.
Keywords: mediated cycloadditions; cobalt mediated; benzo furans; benzo thiophenes ... See more keywords