De Novo 3-(Phenylcarbamoyl) Benzoate Analogues: Efficacy against Multidrug-Resistant S. aureus and Elucidation of the Biodistribution Profile.
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DOI: 10.1021/acs.jmedchem.5c00515
Abstract: This study presents the first design, synthesis, and characterization of a novel library of carboxylate analogues of 3-(phenylcarbamoyl) benzoate (L1-L17) as potent antimicrobial agents targeting Staphylococcus aureus infections. The lead compounds L8, L13, L14, and… read more here.
Keywords: aureus; resistant aureus; phenylcarbamoyl benzoate; benzoate analogues ... See more keywords