Methyl benzoate derivatives as inhibitors of pentose phosphate pathway, which promotes cancer progression and drug resistance: An In Silico study supported By In Vitro results.
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DOI: 10.1002/bab.2322
Abstract: The pentose phosphate pathway (PPP), whose products are vital in biosynthetic events, is targeted in the treatment of many diseases such as cancer and malaria. The objective of this study was to identify new PPP… read more here.
Keywords: cancer; study; phosphate pathway; pentose phosphate ... See more keywords
Methyl benzoate derivatives: in vitro Paraoxonase 1 inhibition and in silico studies
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DOI: 10.1002/jbt.23152
Abstract: Paraoxonase 1 (PON1) can metabolize some compounds such as aromatic carboxylic acid and unsaturated aliphatic esters, arylesters, cyclic carbonate, plucuronide drugs, some carbamate insecticide classes, nerve gases, and lactone compounds. Methyl benzoate has recently been… read more here.
Keywords: inhibition; benzoate derivatives; methyl benzoate; derivatives vitro ... See more keywords
Structures and Chemical Rearrangements of Benzoate Derivatives Following Gas Phase Decarboxylation.
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DOI: 10.1021/jasms.2c00188
Abstract: Decarboxylation of carboxylate ions in the gas phase provides a useful window into the chemistry displayed by these reactive carbanion intermediates. Here, we explore the species generated by decarboxylation of two benzoate derivatives: 2-formylbenzoate (2FBA)… read more here.
Keywords: decarboxylation; gas phase; benzoate derivatives; structures chemical ... See more keywords