Computational investigation, comparative approaches, molecular structural, vibrational spectral, non-covalent interaction (NCI), and electron excitations analysis of benzodiazepine derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-021-04877-z
Abstract: The present work explores the structural parameters and vibrational frequencies as well as molecular interactions of benzodiazepine derivatives, such as clothiapine (CT), clozapine (CZ), and loxapine (LX). Employing fitting experimental data to theoretical results is… read more here.
Keywords: investigation comparative; comparative approaches; benzodiazepine derivatives; computational investigation ... See more keywords
Insight into the corrosion inhibition of new benzodiazepine derivatives as highly efficient inhibitors for mild steel in 1 M HCl: Experimental and theoretical study
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.127428
Abstract: Abstract This work reports the synthesis of two organic compounds based on benzodiazepine derivatives, namely 11-phenyl-2,3,4,10,11,11a-hexahydro-1H-dibenzo[b,e][1,4]diazepine (CSBO) and 11-methyl-11-phenyl-2,3,4,10,11,11a-hexahydro-1H-dibenzo[b,e][1,4]diazepine (TVBO). The Anti-corrosion properties for mild steel (MS) in molar HCl have been investigated by standard… read more here.
Keywords: steel; mild steel; benzodiazepine derivatives; corrosion inhibition ... See more keywords
Benzodiazepine Derivatives as Potent Vasopressin V2 Receptor Antagonists for the Treatment of Autosomal Dominant Kidney Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00567
Abstract: Cyst formation and enlargement in autosomal dominant kidney disease (ADPKD) is mainly driven by aberrantly increased cytosolic cAMP in renal tubule epithelial cells. Because the vasopressin V2 receptor (V2R) regulates intracellular cAMP levels in kidneys,… read more here.
Keywords: dominant kidney; kidney; benzodiazepine derivatives; vasopressin receptor ... See more keywords