Maturational Changes of Gamma-Aminobutyric Acid A Receptors Measured With Benzodiazepine Binding of Iodine 123 Iomazenil Single-Photon Emission Computed Tomography.
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DOI: 10.1016/j.pediatrneurol.2018.02.008
Abstract: BACKGROUND Iodine 123 (I-123) iomazenil is a specific ligand of the central benzodiazepine receptor, which is a part of the postsynaptic gamma-aminobutyric acid A receptor complex. We performed statistical image processing of I-123 iomazenil single-photon… read more here.
Keywords: benzodiazepine receptor; 123 iomazenil; receptor; binding activity ... See more keywords
Blended care to discontinue benzodiazepine receptor agonists use in patients with chronic insomnia disorder: a pragmatic cluster randomized controlled trial in primary care
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DOI: 10.1093/sleep/zsac278
Abstract: Abstract Study Objectives International guidelines recommend using benzodiazepine receptor agonists (BZRA) for maximally four weeks. Nevertheless, long-term use for chronic insomnia disorder remains a common practice. This study aimed to test the effectiveness of blended… read more here.
Keywords: receptor agonists; blended care; trial; benzodiazepine receptor ... See more keywords
Characterisation of concurrent use of prescription opioids and benzodiazepine/Z-drugs in Alberta, Canada: a population-based study
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DOI: 10.1136/bmjopen-2019-030858
Abstract: Objective The objective of this study is to characterise concurrent use of benzodiazepine receptor modulators and opioids among prescription opioid users in Alberta in 2017. Design A population based retrospective study. Setting Alberta, Canada, in… read more here.
Keywords: concurrent use; use; benzodiazepine receptor; study ... See more keywords
Hazardous use of benzodiazepine receptor agonists in psychiatric clinics in China: electronic prescription database study
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DOI: 10.1192/bjo.2022.589
Abstract: Background Benzodiazepine receptor agonists (BZRAs) are commonly used clinically and data on their hazardous use from large populations of psychiatric patients is limited. Aims To assess the current status of hazardous BZRA use and related… read more here.
Keywords: receptor agonists; prescription; benzodiazepine receptor; hazardous use ... See more keywords
Deprescribing benzodiazepine receptor agonists taken for insomnia: a review and key messages from practice guidelines.
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DOI: 10.20452/pamw.4391
Abstract: Long‑term benzodiazepine receptor agonist (BZRA) use for insomnia is common and highly prevalent in adults in all care settings. Evidence syntheses suggest that the therapeutic benefits of benzodiazepines for insomnia are marginal and very short… read more here.
Keywords: deprescribing benzodiazepine; benzodiazepine receptor; receptor agonists; practice ... See more keywords
Evolution of benzodiazepine receptor agonist prescriptions in general practice: A registry-based study
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DOI: 10.3389/fpubh.2022.1014734
Abstract: Background Contrary to most European guidelines, benzodiazepine receptor agonists (BZRA) are often used continuously at a low dosage, being the most common form of long-term use. In Belgium, BZRA use is monitored by analyzing self-report… read more here.
Keywords: general practice; bzra; registry; benzodiazepine receptor ... See more keywords
Benzodiazepine-Receptor Agonist Utilization in Outpatients with Anxiety Disorder: A Retrospective Study Based on Electronic Healthcare Data from a Large General Tertiary Hospital
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DOI: 10.3390/healthcare11040554
Abstract: Benzodiazepine-receptor agonists (BZRAs), including benzodiazepines (BZDs) and drugs related to BZDs (Z-drugs), are commonly used for anxiety, but often have side effects. We retrospectively investigated the utilization and prescription characteristics of BZRAs for patients with… read more here.
Keywords: electronic healthcare; based electronic; utilization; benzodiazepine receptor ... See more keywords
Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2018.16.2.184
Abstract: Objective Suvorexant is a novel hypnotic drug that does not interact with the conventional γ-aminobutyric acid (GABA)-A receptor. We investigated the method by which suvorexant was introduced in insomnia patients who were taking benzodiazepine receptor… read more here.
Keywords: insomnia patients; benzodiazepine receptor; retrospective study; group ... See more keywords