Palladium-Mediated Functionalization of Benzofuran and Benzothiophene Cores
Sign Up to like & getrecommendations! Published in 2018 at "Organometallics"
DOI: 10.1021/acs.organomet.8b00682
Abstract: The palladation reactions of 2-heteroaromatic primary phenethylamines bearing a benzofuran and benzothiophene nuclei have been studied. We have assessed the reactivity of the corresponding dimeric six-membered palladacycles (arising from C–H metalation) toward neutral ligands and… read more here.
Keywords: benzofuran benzothiophene; mediated functionalization; functionalization benzofuran; palladium mediated ... See more keywords
Synthesis of Difluoroalkylated Benzofuran, Benzothiophene, and Indole Derivatives via Palladium-Catalyzed Cascade Difluoroalkylation and Arylation of 1,6-Enynes.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.9b04681
Abstract: A novel and efficient method for the synthesis of difluoroalkylated benzofuran, benzothiophene, and indole derivatives via palladium-catalyzed aryldifluoroalkylation of 1,6-enynes with ethyl difluoroiodoacetate and arylboronic acids has been established. High reaction efficiency, mild conditions, broad… read more here.
Keywords: benzofuran benzothiophene; difluoroalkylated benzofuran; synthesis difluoroalkylated; indole derivatives ... See more keywords