Discovery of novel benzohydroxamate-based histone deacetylase 6 (HDAC6) inhibitors with the ability to potentiate anti-PD-L1 immunotherapy in melanoma
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DOI: 10.1080/14756366.2023.2201408
Abstract: Abstract In this study, a novel series of histone deacetylases 6 (HDAC6) inhibitors containing polycyclic aromatic rings were discovered and evaluated for their pharmacological activities. The most potent compound 10c exhibited high HDAC6 inhibitory activity… read more here.
Keywords: discovery novel; histone; novel benzohydroxamate; hdac6 ... See more keywords