Impact of a drug safety communication on the severity of benzonatate exposures reported to poison centers
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5136
Abstract: Identify if publication of the 2010 drug safety communication (DSC) regarding benzonatate was associated with a decrease in the incidence of severe benzonatate poisonings reported to United States poison centers. read more here.
Keywords: poison centers; drug; benzonatate; drug safety ... See more keywords
The Antitussive Benzonatate Is Not Tumorigenic in Rodent Carcinogenicity Studies
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DOI: 10.1177/0192623318789130
Abstract: Benzonatate is a peripheral oral antitussive that dampens the activity of cough stretch receptors. Rodent carcinogenicity studies were performed in Tg.rasH2 mice and Wistar Han rats. Mice were orally gavaged benzonatate at 10, 30, 75,… read more here.
Keywords: carcinogenicity studies; day; benzonatate; rodent carcinogenicity ... See more keywords
Benzonatate as a local anesthetic
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DOI: 10.1371/journal.pone.0284401
Abstract: Introduction Benzonatate is an FDA-approved antitussive agent that resembles tetracaine, procaine, and cocaine in its chemical structure. Based on structural similarities to known local anesthetics and recent findings of benzonatate exerting local anesthetic-like effects on… read more here.
Keywords: nerve blockade; local anesthetic; nerve; benzonatate ... See more keywords