Catalyst-free synthesis of 1,2,4,5-tetrasubstituted imidazoles from arylamins, benzonitriles, arylglyoxals, and Meldrum’s acid
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DOI: 10.1016/j.tetlet.2018.03.093
Abstract: Abstract An efficient and catalyst-free for the synthesis of 1,2,4,5-tetrasubstituted imidazoles has been developed using a one-pot, two-step reaction of arylamins, benzonitriles, arylglyoxals, and Meldrum’s acid. All the products were obtained in good to excellent… read more here.
Keywords: free synthesis; synthesis tetrasubstituted; arylamins benzonitriles; benzonitriles arylglyoxals ... See more keywords