Rapid and efficient tetrazine-induced drug release from highly stable benzonorbornadiene derivatives.
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DOI: 10.1039/c7cc03477f
Abstract: A novel class of bioorthogonal release reactions based on benzonorbornadiene derivatives was developed. These carrier molecules are highly stable at physiological conditions, but react rapidly with 1,2,4,5-tetrazines, and near-quantitatively release cargo molecules such as drugs… read more here.
Keywords: efficient tetrazine; rapid efficient; highly stable; benzonorbornadiene derivatives ... See more keywords