Articles with "benzopyran fused" as a keyword



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Rationally designed benzopyran fused isoxazolidines and derived β2,3,3-amino alcohols as potent analgesics: Synthesis, biological evaluation and molecular docking analysis.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2016.12.052

Abstract: Based on structure activity analysis of morphine related opiates, we have synthesized some novel benzopyran fused isoxazolidines (2a-e) and derived conformationally constrained β2,3,3-amino alcohols (3a-e), which were evaluated in vivo for their anti-nociceptive activity through acetic… read more here.

Keywords: analysis; benzopyran fused; isoxazolidines derived; amino alcohols ... See more keywords