Biomolecular Interactions of Cytotoxic Ruthenium Compounds with Thiosemicarbazone or Benzothiazole Schiff Base Chelates
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200444
Abstract: Herein we illustrate the formation and characterization of new paramagnetic ruthenium compounds, trans‐P‐[RuCl(PPh3)2(pmt)]Cl (1) (Hpmt=1‐((pyridin‐2‐yl)methylene)thiosemicarbazide), trans‐P‐[RuCl(PPh3)2(tmc)]Cl (2) (Htmc=1‐((thiophen‐2‐yl)methylene)thiosemicarbazide) and a diamagnetic ruthenium complex, cis‐Cl, trans‐P‐[RuCl2(PPh3)2(btm)] (3) (btm=2‐((5‐hydroxypentylimino)methyl)benzothiazole). Agarose gel electrophoresis experiments of the metal compounds… read more here.
Keywords: biomolecular interactions; interactions cytotoxic; ruthenium compounds; ruthenium ... See more keywords
Evaluation of the efficacy of benzothiazole against the red flour beetle, Tribolium castaneum (Herbst).
Sign Up to like & getrecommendations! Published in 2020 at "Pest management science"
DOI: 10.1002/ps.5819
Abstract: BACKGROUND In the context of the resistance development and health risks of currently used fumigants, it is urgent to seek more effective and ecofriendly compounds for stored-product pest control. The microbial volatile compound benzothiazole is… read more here.
Keywords: castaneum; tribolium castaneum; evaluation efficacy; benzothiazole ... See more keywords
Residue behavior and efficacy of benzothiazole in grains under different fumigation conditions.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7536
Abstract: BACKGROUND Benzothiazole was a potential grain fumigant for Tribolium castaneum. However, its safety profile and suitable fumigation conditions remain unknown. Therefore, we investigated the insecticidal efficacy, accumulation and dissipation of benzothiazole in grains (wheat, corn… read more here.
Keywords: benzothiazole grains; efficacy; fumigation conditions; rice ... See more keywords
Synthesis of benzothiazole derivatives as a potent α-glucosidase inhibitor.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.12.021
Abstract: Diabetes is one of the pre-dominant metabolic disorders all over the world. It is the prime reason of mortality and morbidity due to hyperglycemia which is link with numerus obstacles. Delaying absorption and digestion of… read more here.
Keywords: benzothiazole; potent glucosidase; synthesis benzothiazole; derivatives potent ... See more keywords
Exploring biological efficacy of novel benzothiazole linked 2,5-disubstituted-1,3,4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization, inhibition, molecular docking, molecular dynamics and Monte Carlo based QSAR studies.
Sign Up to like & getrecommendations! Published in 2021 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2021.104876
Abstract: In an effort to explore a class of novel antidiabetic agents, we have made an effort to synergize the α-amylase inhibitory potential of 1,3-benzothiazole and 1,3,4-oxadiazole scaffolds by combining the two into a single structure… read more here.
Keywords: exploring biological; benzothiazole; inhibition; amylase ... See more keywords
Benzothiazole modified rhodol as chemodosimeter for the detection of sulfur mustard simulant.
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DOI: 10.1016/j.talanta.2018.06.066
Abstract: In this paper, we introduced a new sensor for detecting sulfur mustard (SM) and its simulant through the functionalization of a rhodol chromophore with benzothiazole, followed by thionation of the spirolactam. The synthesized chemodosimeter (RHBT)… read more here.
Keywords: benzothiazole; sulfur mustard; mustard simulant; detection sulfur ... See more keywords
N-Heterocyclic carbene catalyzed aza-benzoin reaction for access to α-aminoketone molecules containing benzothiazole fragments
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DOI: 10.1016/j.tet.2021.132311
Abstract: Abstract An N-Heterocyclic carbene (NHC) catalyzed aza-benzoin reaction of benzothiazole-2-carboxaldehydes and N-sulfonylimines is reported for the first time. The target benzothiazole-containing aminoketone products bearing different substituents and substitution patterns can be obtained in good to… read more here.
Keywords: aza benzoin; benzothiazole; catalyzed aza; benzoin reaction ... See more keywords
Rational design of the benzothiazole-based fluorescent scaffold for tunable emission
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.03.029
Abstract: Abstract The 2-(2-hydroxyphenyl)-benzothiazole (HBT) fluorophore has attracted considerable attention due to its excited-state intramolecular proton transfer (ESIPT) based emission and its large Stokes shift. However, this fluorophore possesses several disadvantages including low quantum yield and… read more here.
Keywords: benzothiazole based; benzothiazole; rational design; emission ... See more keywords
Degradation of amyloid peptide aggregates by targeted singlet oxygen delivery from a benzothiazole functionalized naphthalene endoperoxide.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc07133e
Abstract: Aggregate structures formed by amyloid-β (Aβ) are correlated with the progression of pathogenesis in Alzheimer's disease. Previous works have shown that photodynamic photosensitizers were effective in oxidatively degrading amyloid-β aggregates and thus decreasing their cytotoxicity… read more here.
Keywords: singlet oxygen; amyloid peptide; benzothiazole; oxygen ... See more keywords
Insertion Reaction of 2-Halo-N-allylanilines with K2S Involving Trisulfur Radical Anion: Synthesis of Benzothiazole Derivatives under Transition-Metal-Free Conditions
Sign Up to like & getrecommendations! Published in 2020 at "Synthesis"
DOI: 10.1055/s-0040-1706104
Abstract: A synthesis of benzothiazole derivatives through the reaction of 2-halo-N-allylanilines with K2S in DMF is developed. The trisulfur radical anion S3·–, which is generated in situ from K2S in DMF, initiates the reaction without transition-metal… read more here.
Keywords: benzothiazole; synthesis benzothiazole; reaction halo; benzothiazole derivatives ... See more keywords
Benzothiazole-based Compounds in Antibacterial Drug Discovery.
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DOI: 10.2174/0929867324666171009103327
Abstract: Numerous compounds with a benzothiazole scaffold that have been described in the literature show promising activities against several Gram-positive and Gramnegative bacteria, and also against Mycobacterium tuberculosis. Benzothiazole-based antibacterial compounds bind to different biological targets… read more here.
Keywords: bacterial cells; benzothiazole; antibacterial drug; benzothiazole based ... See more keywords