Synthesis of 2,2-difluoro-3H-benzothiophen-3-ol via a difluorocarbene insertion reaction, investigating the scope for further derivatization
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DOI: 10.1080/00397911.2019.1614629
Abstract: Abstract A simple, and efficient synthesis of 2,2-difluoro-3H-benzothiophen-3-ol using readily available sodium chlorodifluoroacetate (SCDA) is reported. We also explore new chemistry of these difluoro compounds. The salient feature of this approach includes operational simplicity and… read more here.
Keywords: difluoro benzothiophen; benzothiophen via; synthesis difluoro; difluoro ... See more keywords