Synthesis and biological evaluation of novel 1,2,3-benzotriazin-4-one derivatives as leukotriene A4 hydrolase aminopeptidase inhibitors
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DOI: 10.1016/j.cclet.2016.12.014
Abstract: Abstract A series of novel 1,2,3-benzotriazin-4-one derivatives were designed, synthesized and their inhibitory activities against leukotriene A 4 hydrolase aminopeptidase in vitro were evaluated. Many compounds showed moderate to good activities at the concentration of… read more here.
Keywords: leukotriene hydrolase; one derivatives; hydrolase aminopeptidase; benzotriazin one ... See more keywords