Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y14R antagonists with anti-gout potential.
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DOI: 10.1016/j.ejmech.2021.113933
Abstract: The P2Y14 nucleotide receptor, a subtype of P2Y receptors, is implicated in many human inflammatory diseases. Based on the identification of favorable residues of two screening hits in the almost symmetrical P2Y14 binding domain, we… read more here.
Keywords: benzoxazole acetamide; p2y14r antagonists; computational studies; phenyl benzoxazole ... See more keywords