An NHC-catalyzed [3+2] cyclization of β-disubstituted enals with benzoyl cyanides.
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DOI: 10.1039/d2cc04025e
Abstract: The NHC-catalyzed asymmetric [3+2] cyclization of benzoyl cyanides to homoenolate generated in situ from enals was reported. This methodology leads to the efficient construction of a series of chiral cyclic compounds bearing vicinal quaternary stereocenters… read more here.
Keywords: catalyzed cyclization; disubstituted enals; nhc catalyzed; benzoyl cyanides ... See more keywords