Electrochemical Amidation: Benzoyl Hydrazine/Carbazate and Amine as Coupling Partners.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02626
Abstract: An electrochemical amidation of benzoyl hydrazine/carbazate and primary/secondary amine as coupling partners via concomitant cleavage and formation of C(sp2)-N bonds has been achieved. This methodology proceeds under metal-free and exogenous oxidant-free conditions producing N2 and… read more here.
Keywords: electrochemical amidation; amine coupling; amidation benzoyl; benzoyl hydrazine ... See more keywords
N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25102268
Abstract: Based on the isosterism concept, we have designed and synthesized homologous N-alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides (from C1 to C18) as potential antimicrobial agents and enzyme inhibitors. They were obtained from 4-(trifluoromethyl)benzohydrazide by three synthetic approaches and characterized by… read more here.
Keywords: alkyl trifluoromethyl; trifluoromethyl benzoyl; hydrazine carboxamides; benzoyl hydrazine ... See more keywords