N2,N9-Bis(Substituted benzyl)-β-Carbolineum Bromides as Potential Anticancer Therapeutics: Design, Synthesis, Cytotoxicity, Drug-DNA Intercalation and In-Silico Binding Properties
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DOI: 10.1016/j.molstruc.2021.130771
Abstract: Abstract The present study reports a series of novel N2,N9-bis(substituted benzyl)-β-carbolineum bromides (4a-f) synthesized from L-tryptophan in three steps with excellent yields (>80%). The structures of synthesized compounds 4a-f were confirmed by 1H- and 13C-NMR,… read more here.
Keywords: dna intercalation; bis substituted; carbolineum bromides; benzyl carbolineum ... See more keywords