Articles with "benzyl dioxopyrrolidin" as a keyword



N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug

Sign Up to like & get
recommendations!
Published in 2019 at "Neurotherapeutics"

DOI: 10.1007/s13311-019-00773-w

Abstract: In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) as a broad-spectrum hybrid anticonvulsant which showed potent protection across the most important animal acute seizure models such as the maximal electroshock (MES) test, the subcutaneous… read more here.

Keywords: dioxopyrrolidin propanamide; benzyl dioxopyrrolidin; ptz; test ... See more keywords