Molecular Insights into the Translesion Synthesis of Benzyl-Guanine from Molecular Dynamics Simulations: Structural Evidence of Mutagenic and Nonmutagenic Replication.
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DOI: 10.1021/acs.biochem.6b01247
Abstract: DNA can be damaged by many compounds in our environment, and the resulting damaged DNA is commonly replicated by translesion synthesis (TLS) polymerases. Because the mechanism and efficiency of TLS are affected by the type… read more here.
Keywords: molecular dynamics; dna; translesion synthesis; replication ... See more keywords