Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer
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DOI: 10.3390/molecules28020840
Abstract: It has been shown that phosphodiesterase 5 (PDE5) inhibitors have anticancer effects in a variety of malignancies in both in vivo and in vitro experiments. The role of cGMP elevation in colorectal carcinoma (CRC) has… read more here.
Keywords: benzylaminoacridine derivatives; inhibition; dual inhibitors; derivatives dual ... See more keywords