8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation.
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DOI: 10.1016/j.bioorg.2020.104033
Abstract: A library of 34 novel compounds based on a xanthine scaffold was explored in biological studies for interaction with adenosine receptors (ARs). Structural modifications of the xanthine core were introduced in the 8-position (benzylamino and… read more here.
Keywords: scaffold variations; variations selective; selective ligands; benzylaminoxanthine scaffold ... See more keywords