Articles with "benzylated pyrrolidin" as a keyword



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Novel benzylated (pyrrolidin-2-one) / (imidazolidin-2-one) derivatives as potential Anti-Alzheimer's agents: Synthesis and Pharmacological investigations.

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Published in 2020 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.0c00403

Abstract: A series of N-benzylated (pyrrolidin-2-one) / (imidazolidin-2-one) derivatives were synthesized and evaluated for anti-Alzheimer's activity. The analogs were designed and synthesized based on lead compound donepezil, which is currently prescribed as a major drug for… read more here.

Keywords: benzylated pyrrolidin; one imidazolidin; pyrrolidin one; imidazolidin one ... See more keywords