Catalytic Asymmetric Benzylation of Azomethine Ylides Enabled by Synergistic Lewis Acid/Palladium Catalysis.
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DOI: 10.1021/acs.orglett.2c00865
Abstract: The synergistic chiral Lewis acid/achiral Pd catalyst system was successfully applied in the enantioselective benzylation of various imine esters, giving a range of α-benzyl-substituted α-amino acid derivatives in satisfactory yield with excellent enantioselectivity. It is… read more here.
Keywords: lewis; asymmetric benzylation; lewis acid; benzylation azomethine ... See more keywords