Dual immuno-renal targeting of 7-benzylidenenaltrexone alleviates lupus nephritis via FcγRIIB and HO-1
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DOI: 10.1007/s00109-018-1626-9
Abstract: Known as a selective δ1 opioid receptor (DOR1) antagonist, the 7-benzylidenenaltrexone (BNTX) is also a DOR1-independent immunosuppressant with unknown mechanisms. Here we investigated if BNTX could be beneficial for diseased MRL/lpr lupus mice. We treated… read more here.
Keywords: p38 mapk; benzylidenenaltrexone; via riib; lupus nephritis ... See more keywords