Design, synthesis, molecular docking and anticancer evaluations of 5-benzylidenethiazolidine-2,4-dione derivatives targeting VEGFR-2 enzyme.
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DOI: 10.1016/j.bioorg.2020.104059
Abstract: Novel series of 5-benzylidenethiazolidine-2,4-dione derivatives 4a-c-8a-f were designed, synthesized and evaluated for anticancer activity against HepG2, HCT-116 and MCF-7 cell lines. MCF-7 was the most sensitive cell line to the influence of the new derivatives.… read more here.
Keywords: benzylidenethiazolidine dione; dione derivatives; anticancer; cell ... See more keywords