Lineage‐Specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early‐Diverging Eudicots
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DOI: 10.1002/advs.202309990
Abstract: Menispermaceae species, as early‐diverging eudicots, can synthesize valuable benzylisoquinoline alkaloids (BIAs) like bisbenzylisoquinoline alkaloids (bisBIAs) and sinomenines with a wide range of structural diversity. However, the evolutionary mechanisms responsible for their chemo‐diversity are not well… read more here.
Keywords: specific cyp80; benzylisoquinoline; diverging eudicots; expansion ... See more keywords
Advancements in Microbial Cell Engineering for Benzylisoquinoline Alkaloid Production.
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DOI: 10.1021/acssynbio.4c00599
Abstract: Benzylisoquinoline alkaloids (BIAs) are a class of natural compounds found in plants of the Ranunculaceae family, known for their diverse pharmacological activities. However, the extraction yields of BIAs from plants are limited, and the cost… read more here.
Keywords: advancements microbial; benzylisoquinoline; cell engineering; microbial cell ... See more keywords
Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.01058
Abstract: O- and N-methylations are ubiquitous and recurring features in the biosynthesis of many specialized metabolites. Accordingly, the methyltransferase (MT) enzymes catalyzing these modifications are directly responsible for a substantial fraction of the vast chemodiversity observed… read more here.
Keywords: origins functional; benzylisoquinoline alkaloid; diversity; benzylisoquinoline ... See more keywords